Retatrutide Injectables About
1. General Chemical Description
This is a synthetically modified, long-acting peptide compound acting as a GLP-1R/GIPR/GCGR triple receptor agonist. The free acid form has the CAS number 2381089-83-2, a molecular formula of CHNO, and a molecular weight of 4731.33; it is commonly prepared as a sodium salt to enhance water solubility and stability. The molecular structure incorporates a fatty acid side-chain modification, significantly extending its in vivo half-life and enabling once-weekly subcutaneous administration.
2. Physical Properties
It appears as a white to off-white, loose lyophilized powder. It is readily soluble in pure water and weakly alkaline PBS buffer, soluble in DMSO, and virtually insoluble in organic solvents such as ethanol, acetonitrile, and acetone. It is highly hygroscopic and sensitive to temperature and light. The HPLC purity is 98.0% for reagent-grade material, while pharmaceutical research-grade material can exceed 99.0%.